Representing a WHOLE continent with such diversity like South America is very difficult. Or at least, doing it with accuracy is. There are 4280932480932840923 OCs which represent South America and they're all just like HOW ABOUT NO?????? like, seriously, I haven't seen one with full accurate features, but that's because it's practically impossible to represent a whole continent. BUT OK, in case you don't really care and want to do it anyways (way 2 go risk-taker), here are a few tips.
Languages: South America is not only spanish speaking countries, you also have to count Brazil (portuguese) and the Caribbean (english, french, dutch, creole